The current study investigated the Ethiopian sugarcane bagasse during its delignification using the Kraft pulping process and bleaching by single stage hydrogen peroxide process. The multilevel categoric experimental design was used to appraise the effects of the independent process variables (temperature, NaOH concentration, and time) on the pulp yield and kappa number during the Kraft pulping process. The central composite experimental design of response surface methodology was used to appraise the effects of independent bleaching variables (bleaching temperature, H2O2 concentration, and time) on the pulp yield, brightness, and whiteness during the bleaching process. The optimal pulp yield was 38.41% with 17.68 kappa number. The bleached pulp yield for the pulp with kappa number of 17.68 and the pulp with kappa number of 8.41 were 84.12% and 83.91%, respectively. The brightness and whiteness for the pulp with kappa number of 17.68 were 61.92% and 85.36%, respectively. Similarly, for the pulp with a kappa number of 8.41, the brightness and whiteness were 68.35% and 91.43%, respectively. Paper from the pulp with kappa number of 17.68 has higher tensile, burst, and tear strength. The study shows the promising utilization of the Ethiopian sugarcane bagasse for paper production via the Kraft delignification and single stage hydrogen peroxide bleaching.